The AACR-Novocure Career Development Award for Cancer Research represents a joint effort to promote and support early-career investigators who are conducting innovative research focused on Tumor Treating Fields (TTFields; intermediate frequency low intensity alternating electric fields that disrupt cell division in cancer cells) as well as to encourage early-career investigators to enter the TTFields research field. The Inovitro® system (which will provided by Novocure if needed) must be included in the experimental design. Training on the use of Inovitro® system will be provided by Novocure if needed. Note that inter-laboratory collaboration is encouraged particularly for applicants new to TTFields research.
These grants are intended to provide a deeper understanding of the mechanisms of action of this novel anti-cancer treatment modality and to accelerate the development of new treatment strategies to advance therapeutic options for cancer. The research proposed for funding may be basic or translational in nature; however studies promoting the transition of in vitro work into in vivo systems combination therapies involving TTFields or translational projects bringing treatments involving TTFields into the clinic will be prioritized.
Each award provides $300 000 over three years for expenses related to the research project which may include salary and benefits of the grant recipient and any collaborators postdoctoral or clinical research fellows graduate students and/or research assistants; research/laboratory supplies; equipment; travel; publication charges for manuscripts that pertain directly to the funded project; other research expenses; and indirect costs.