Download the 2026-2027 PBTF Research Program guide here.
Please note: Proposals without a clear data strategy will not be funded
For more than 35 years, the Pediatric Brain Tumor Foundation has worked at the intersection of research, family support, and advocacy – tumor-agnostic, institution-agnostic, and relentlessly committed to children and families throughout their entire journey.
We often describe our mission in three words: Care. Cure. Thrive. Research is the engine that powers all three. It has the potential to improve the care children receive today, deliver better treatments that help them live longer and thrive, and ultimately bring us closer to cures for every pediatric brain tumor.
Beginning in 2026, PBTF is shifting from funding individual, standalone projects to strategically building the shared data and infrastructure that unlocks better outcomes for children with brain tumors. Technology and computational approaches are now central to that strategy; every funded project must include a defined plan for how it applies AI/ML and contributes to the shared data ecosystem.
Every funded project must contribute to and draw from this shared, harmonized data ecosystem, and we thank our research community for its partnership in getting there. Throughout the year, the PBTF advances a diverse portfolio of research projects, programs and initiatives towards our mission to improve outcomes, including foundation-initiated challenge grants (RFPs), collaborative funding programs with like-minded organizations submitted through our website.